Duac Gel

Duac Gel is a medication used for mild to moderate acne eruptions on the skin. It contains the ingredient benzoyl peroxide and clindamycin (an antibiotic). This medicine directly treats acne by killing the bacteria Propionebacterium acnes on the skin because both ingredients have antibacterial properties. The benzoyl peroxide will also help the skin surface to shed slightly and clear the surface layer, thereby helpingtreat acne and promote healing of the skin.
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Images for illustrative purposes only

Duac Gel

Duac Gel is a medication used for mild to moderate acne eruptions on the skin. It contains the ingredient benzoyl peroxide and clindamycin (an antibiotic). This medicine directly treats acne by killing the bacteria Propionebacterium acnes on the skin because both ingredients have antibacterial properties. The benzoyl peroxide will also help the skin surface to shed slightly and clear the surface layer, thereby helpingtreat acne and promote healing of the skin.


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DuacGel is a special topical medicine for acne which helps destroy acne bacteria as well as treat blackheads and whiteheads. It helps reduce spots on the face and make the skin clear. The benzoyl peroxide will also help the skin surface to shed slightly and clear the surface layer of any signs of acne. 

The Duac Gel shows its effect within six to twelve weeks of treatment usually.

Duac Gel contains two active ingredients - benzoyl peroxide and clindamycin 

Benzoyl peroxide is a keratolytic medicine. This ingredient breaks down the protein called keratin in the skinsurface. When applied to the skin, it results in breaking down and shedding the top layer of the skin. This helps break down existing blackheads and whiteheads, prevents new ones and unblocks the sebaceous glands. 

Clindamycin is an antibiotic which helps treat infections associated with bacteria. Applying clindamycin to the skin helps reduce the eruption of bacteria, reduces the inflammation of the sebaceous glands, and helps the skin heal. 

Duac should be applied once a day, preferably in the evening. However, your prescription will advise the dose which is best suited for your condition and age.  

 If you miss the dose, apply as soon as you remember. But if it's already time for the next one, just apply that dose and do not use a double dose.

Before you apply the Duac Gel, wash and clean the area you are treating thoroughly with warm water and pat the area dry. Squeeze the necessary quantity of the gel from the tube and apply it to your face. An oil-free face wash designed for acne is useful. 

Duac Gel should not be used by: 

  • People who have sensitive or eczema-prone skin. 

  • People who have a history of inflammation in their intestines (enteritis), who suffer from ulcerative colitis (a condition in which the large intestine becomes inflamed due to antibiotic treatment). 

  • People who have recently made use of any other medicines which contain antibiotics such as the ingredients clindamycin or erythromycin. It is possible that with regular exposure to such antibioticsthe acne bacteria on your skin may develop resistance to clindamycin which would make the DuacGel less effective. 

  • People who are allergic to any of the ingredients of the gel. 

Common side effects of the gel include: 

  • Itching 

  • Redness 

  • Burning sensation 

  • Dryness or mild peeling of the skin where the gel is applied 

  • Dermatitis 

A few precautions while using Duac Gel include: 

  • Use sunscreen outdoors as the medicine may make your skin more sensitive to sunlight. 

  • Avoid using any skincare products which may have a chance of drying your skin.  

Do not use the gel with:  

  • Other products which contain other antibiotics especially erythromycin or clindamycin 

  • Products that contain tretinoinisotretinoin or tazarotene 

  • Oral medication which contains isotretinoin 

You can safely purchase Duac Gel online at MedsNow. Firstly, you will have an online consultation with one of our cliniciansif Duac Gel is the right medicine for you, your order will be supplied.  

Can I Use Make-Up After Applying Duac?
You may use non-greasy makeup after the gel has dried completely.

Can I Use Duac After Shaving?
It is recommended to leave a few hours of gap between using the gel and shaving.

Duac Is Making My Skin Irritated, What Should I Do?
Unfortunately, the benzoyl peroxide component of the gel can sometimes cause some skin irritation via its mechanism of action. If this is mild, then please trial a moisturiser initially or reducing the application temporarily to every other night until your skin gets more accustomed to the treatment. If the irritation persists or seems severe then please arrange a review with our team to discuss further.

Is Duac Safe To Use Whilst Pregnant Or Breastfeeding?
No, you must not use the gel if you are pregnant or breastfeeding.

How Long Should I Use Duac?
It is usually recommended for 6-12weeks. If there is no improvement after 12 weeks, please consult our team to discuss if another treatment may be more effective for you.

Should I Keep Using My Moisturiser With Duac?
A moisturiser helps prevent dry skin, which is important for helping to keep the skin healthy and hydrated whilst using acne treatments which can sometimes be a little more irritant to the skin. You can apply moisturiser over a layer of Duac after it has dried. However, you should always try to use a simple alcohol-free moisturiser.

Will Using Duac Cause Dry Skin?
Yes, it is a known side effect of the gel. This can be managed by using a simple light moisturiser once a day which should help your skin feel more like its healthy normal self.

How Should I Store Duac?
Keep the medication in a cool, dry place below 25°C. Keep it out of reach of children.

Can I Still Drink Alcohol When Using Duac?
There is no known interaction between drinking alcohol and medicine.

Can I Buy Duac Over-The-Counter?
No, it is a prescription-only medicine.

Does Duac Fade Acne Scars?
It may fade acne scars in some cases. To treat acne scars in a more focussed way we would recommend trying azelaic acid or niacinamide, both of which are available from MedsNow and can be used safely alongside the Duac to help you achieve your skincare goals.

What Happens If You Use Too Much Duac?
It may cause skin irritation and dryness. Always use the amount of medicine as recommended to you by your prescription. If you use too much Duac, please try to wash it off and cleanse the area.

Does Duac Work For Hormonal Acne?
It is known to be effective for any form of adult acne – hormonal or otherwise. If your acne is hormonal you may benefit from using Duac as part of a broader treatment plan. Please get in touch with our team to discuss this in more detail.

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