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Zoely 2.5/1.5mcg

Zoely is a prescription medication usually recommended as a hormonal contraceptive. It works under a combination of two active ingredients. Estradiol is a variant of the natural estrogen and Nomegestrol, which is a synthetic form of progesterone found in the body.
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Zoely 2.5/1.5mcg

Zoely is a prescription medication usually recommended as a hormonal contraceptive. It works under a combination of two active ingredients. Estradiol is a variant of the natural estrogen and Nomegestrol, which is a synthetic form of progesterone found in the body.


Zoely tablets are hormonal contraceptive pills formulated with a combination of two active ingredients. The first is estradiol, a form of estrogen found in the body, while the second is nomegestrol, a synthetic form of progesterone. Both are synthetic versions of the naturally occurring female sex hormones, estrogen, and progesterone. Zoely is usually recommended to prevent pregnancy, along with overcoming problems of heavy, painful, or irregular periods. It is popularly known as 'the pill' or combined oral contraceptive.

Zoely tablets are highly beneficial in effectively preventing pregnancy by:

  • tricking your ovaries into believing that ovulation has occurred, preventing the release of an egg for fertilization by the sperm.
  • making it difficult for the sperm to enter the uterus by thickening the mucus at the neck of the uterus.
  • preparing the lining of the womb to not be conducive for the attachment of a fertilized egg.

When taken every day as per the prescribed dosage, Zoley has proven to effectively help people avoid unwanted pregnancy by synthetically mimicking the effects of the naturally present female sex hormones.

Combined oral contraceptive pills like Zoely usually function by overriding the natural menstrual cycle in people with vaginas. A menstrual cycle induces changes in the levels of the sex hormones throughout each month. These hormones lead to the release of an egg from the ovaries, during a phase called ovulation, to prepare the womb lining for a possible pregnancy. If the egg does not get fertilized at the end of the cycle, the hormonal levels fall, leading to monthly menstruation when the womb lining sheds.

Now, Zoley provides a daily dose of hormones that trick your body that ovulation has already happened. It thus prevents an egg from ripening and releasing from the ovaries monthly in the first place. Both estradiol and nomegestrol work together to increase the thickness of the natural mucus present at the neck of your womb, making it difficult for the sperm to enter the womb or fertilize an egg. The hormones also function to alter the quality of the womb lining making it less likely for a fertilized egg to get implanted.

Follow the instructions below to take Zoley:

  • Zoely is an everyday pill to be taken once daily. You can buy the tablets in a 28 tablets strip.
  • Each of these strips will have 24 small white active tablets and 4 small yellow inactive tablets.
  • You must follow the order of taking the tablets as specified on the pack.
  • Begin with the tablet marked one and continue accordingly. The package comes with self-adhesive strips, each mentioning a different day of the week.
  • You will be able to understand on which day to take each tablet.
  • To begin using the tablet, pull out a pill that is marked with the day you start, for instance, “Fri" for Friday. Make sure you stick that pill to the top of the strip so that the first day is mentioned with the pill marked ‘start.
  • The four inactive tablets will help you get used to taking a pill at the same time every day.
  • You can take Zoely tablets with or without food.
  • Try taking your pill at the same time daily to remember.

You will begin the 28 days strip with 24 active tablets taken once daily for 24 days followed by 4 inactive tablets for the last 4 days.

Zoley is suitable for people who are looking for combined oral contraceptives. Certain groups should not choose a hormonal contraceptive like Zoley. These include people who are:

  • Breastfeeding, the combined pill shouldn't be taken until six months after birth.
  • Suffering from a blood clot in a vein for instance in the leg (deep vein thrombosis) or lungs (pulmonary embolism).
  • Facing blood disorders that raise the risk of blood clots in the veins.
  • Having sclerosing treatment for varicose veins.
  • With two or more other risk factors for getting a blood clot in a vein, eg family history, obesity, smoking, or long-term immobility.
  • At the risk of heart attack, stroke, or mini-stroke caused by a blood clot in an artery.
  • Facing the risk of angina, heart valve disease, or an irregular heartbeat.
  • With moderate to severe high blood pressure i.e. hypertension.
  • Smoking excessively.
  • Over 50 years of age.
  • Suffering from severe diabetes, with complications affecting the eyes, kidneys, or nerves.
  • At the risk of getting migraines regularly lasting over 72 hours despite treatment, or treat them with ergot derivatives.
  • Suffering from breast cancer or a history of breast cancer
  • Facing abnormal vaginal bleeding with an unknown cause.
  • With a long-term condition called systemic lupus erythematosus (SLE).
  • Having a history of excess urea in the blood that damages the red blood cells.
  • Facing active liver disease, eg liver cancer, hepatitis.
  • With disorders of bile excretion that cause jaundice
  • Enduring gallstones.
  • With a history of jaundice, hearing disorders, rashes during a previous pregnancy, used sex hormones earlier.
  • At the risk of rare hereditary problems of galactose intolerance, etc. because Zoely tablets contain lactose

Like all medicines, Zoley has its own set of possible side effects that may affect individuals in different ways. However, each person doesn't need to experience them. Listed below are some of the side effects associated with this medicine:

  • Abdominal pain
  • Weight changes
  • Retention of water in the body tissues (fluid retention)
  • Vaginal thrush (candidiasis)
  • Change in menstrual bleeding, usually lighter periods or sometimes stopping periods
  • Steepening of corneal curvature, which may make contact lenses uncomfortable
  • Menstrual spotting or breakthrough bleeding
  • Depression
  • Migraine
  • Nausea and vomiting
  • Breast tenderness and enlargement
  • Decreased sex drive
  • A rise in blood pressure
  • Disturbance in liver function
  • Gallstones
  • Skin reactions
  • Irregular brown patches on the skin, usually of the face (chloasma)
  • Blood clots in the blood vessels (eg, DVT, pulmonary embolism, heart attack, stroke)

The side effects listed above may not include all of the side effects reported by the medicine's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

Remember that Zoley differs from other contraceptive pills which come as 21 active pills followed by a pill-free week.

  • The inactive pills also function as a contraceptive provided you take the active pills correctly as per the schedule.
  • It is ideal to start taking the pill right from the first day of your menstrual cycle. This way the medication will start protecting you against unwanted pregnancy immediately.
  • You don’t have to use any other method of contraception while you are taking Zoely.
  • For people with a short menstrual cycle, you need to start taking the pills before the fifth day of your period for it to start acting in your body.
  • Starting the pill at any other time in your cycle will not protect you from pregnancy and You might have to use other forms of contraception.
  • If you have just given birth but are not breastfeeding, you may begin with Zoley after 21 days of birthing.
  • Starting to take the pill immediately after a miscarriage or abortion at under 24 weeks will immediately provide you with protection against pregnancy. If you start taking the pill more than seven days after a miscarriage or abortion, you should use extra contraception for the seven days of taking the pills.
  • If you missed a tablet or begin your dosage a day later, consume the missed pill as soon as you remember even if you have to take two pills at the same time. Then continue taking the rest of the pack as scheduled. You are still protected from pregnancy and you don’t have to use extra contraception.
  • Then continue taking the rest of the Zoely pills in the pack as scheduled.
  • If less than seven pills are remaining in the Zoely strip considering your last missed pill, finish the current pack and start with a new one right away without the four inactive pills.
  • Remember that vomiting within two hours of taking a pill will restrict the medicine from being absorbed into the bloodstream.
  • Take another pill as soon as you feel better and take the next pill at your usual time. You will still be protected against pregnancy.
  • Please note that Zoely does not offer protection against sexually transmitted infections. Make sure to use condoms for additional protection.
  • Women using Zoely for the first time might face irregularity in menstruation including spotting, breakthrough bleeding, or missed period.
  • If you miss your menstruation for two consecutive months, take a test to rule out pregnancy before starting the next month’s contraceptive cycle.

You can place your order for Zoley online with MedsNow online pharmacy to ensure that you receive only reliable and safe products. Before you place your order, you will have to take an online consultation to ensure that this medicine is the ideal remedy for you. Once you fill the consultation form, your order will be dispatched and delivered discreetly to your doorstep.

Does Zoely make you put on weight?
Yes, fluid retention being one of the side effects of Zoley, it might cause weight gain.

Does Zoely cause depression?
Combined oral contraceptives like Zoley and progesterone-only minipills can lead to more risk of depression and anxiety than other choices of birth control.

What pill is similar to Zoely?
Drospirenone or ethinylestradiol (Yasmin) have similar contraceptive efficacy to Zoley.

Can I take Zoely if I'm breastfeeding?
The hormones in Zoley might lead to a reduction in breast milk production. That's why it is not recommended for women who are breastfeeding.

Can Zoely take away your period?
You may alter and delay your period by continuing with the active tablets of Zoley once you finish your current pack.

Is Zoely safe?
Yes, this combined contraceptive is a safe and effective way to prevent unwanted pregnancy, provided you follow the instructions precisely when taking the pills.

Can you get pregnant on Zoely?
Zoley contains estradiol, a form of natural estrogen that is missing in other pills that usually contain the synthetic estrogen ethinylestradiol. When taken as per the ideal dosage the chance of pregnancy becomes lowers down extremely.

Do you have a period on Zoely?
Your period may begin during the 4 days when you take the yellow inactive tablets meant for the withdrawal bleed. A period may usually start on days 2-3 after you take the last white tablet and continue till the next strip is started.

How long does it take Zoely to work?
Once you begin with the correct day tablet while on your periods, Zoley will begin to work immediately to prevent unwanted pregnancy.

How to stop taking the combined pill - Zoely?
You can stop taking Zoley any time you plan to get pregnant. However, if you are unsure of its effects, talk to your doctor.

What happens if you miss one Zoely pill?
If your missed pill is less than 12 hours late, the pill should be taken immediately. You can take two pills together if you have to substitute the missed one. Make sure you have not missed any pill from the 28 days strip.

What happens if too many Zoely tablets are taken (overdose)?
There is a lack of evidence to prove any serious harmful effects of overdosing Zoley. If you think you have taken too much you might experience sickness, vomiting or vaginal bleeding.

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