Jext is an emergency usage pen device pre-filled with adrenaline (or epinephrine) to be used in life-threatening allergy (anaphylaxis). Jext is filled with liquid containing adrenaline and works faster to provide immediate relief in case of anaphylaxis. Jext is the pen device intended for self-administration or caregiver or family member, in emergency condition only. People having a history of anaphylaxis should carry a Jext device all the time.

Jext is a pre-filled pen device that contains adrenaline or epinephrine. Jext is to be used in case of severe acute anaphylaxis, i.e., severe acute allergic reaction to a food item, chemical or insect bite or drugs. Usage of Jext is for emergency purpose only.

Adrenaline or epinephrine is naturally secreted in the human body under stress condition or in emergencies. Adrenaline offers immediate relief from the hypersensitivity reactions to allergies or anaphylaxis. Adrenaline is a potent vasoconstrictor, as a result of which it offsets the increased vascular permeability and vasodilatation in anaphylactic shock. Vasodilation and enhanced vascular permeability in anaphylactic shock characteristically result in hypotension and fluid retention (or swelling). Thus, Jext is used to treat anaphylaxis.

• Jext is an emergency usage medicine only.
• People having a history of anaphylaxis should always carry Jext with them.
• In addition to epinephrine, Jext also contains sodium metabisulphite and sodium chloride. Hence, people allergic to sodium metabisulphite should not use it.
• People allergic to adrenaline should avoid using Jext.
• People with high heart rate, atherosclerosis or any other severe heart disease should avoid using Jext.
• Women in labour should not be given Jext.
• People who are under general anaesthesia for any surgical procedure should not be administered Jext.
• Glaucoma patient should also avoid Jext.

Jext is a single dose and single usage pen device and is available in two strengths, 150 µg and 300 µg. Jext is to administer intramuscularly on the outer thigh.

• For adults and children above 30Kg body weight should be administered 300 µg via the intramuscular route.
• For children, 15- 30 Kg body weight should be given 150µg dose to treat severe allergic reaction or anaphylaxis.

The dose of Jext is dependent upon the bodyweight of the patient.

Before using Jext, the structure and parts of the Jext should be clear. The following steps are to be followed for the usage of Jext.

1. Hold the Jext pen device tightly in your hand with your thumb near to yellow cap. Depending upon your ease of usage, either of the hand could be used.
2. Remove the yellow cap with the help of another hand.
3. On the outer thigh, place the Jext device at a 90º position, with a black tip touching the outer thigh.
4. Now, press the black tip of Jext firmly on the outer thigh muscle until a ‘click’ sound is heard. Continue holding the device at the same position for at least 10 sec and then remove it. The blacktip of the Jext will automatically extend and hide the needle.
5. Post removal of Jext, massage gently at the site of the administration.

Pregnant and breastfeeding women should altogether avoid using Jext.

People having any of the following condition are at risk of increased side effects-

• Arrhythmia or other heart diseases
• Diabetes
• Overactive thyroid
• Glaucoma
• Allergy towards sodium metabisulphite
• Geriatric patient
• High blood calcium level
• Low blood potassium level
• Tumour of the adrenal gland

Common side effects related to Jext usage are:
faster heartbeat or tachycardia, arrhythmias, sweating, headache, difficulty in breathing, anxiety and nervousness, shaking, tremor of hands, dizziness, weakness, nausea paleness, palpitations, and vomiting.

Concommitttent usage of Jext with ß-blockers (like propranolol), quinidine, antidepressants (MAO-inhibitors like phenelzine, isocarboxazid, tranylcypromine, moclobemide), digoxin, rasagiline, selegiline, entacapone and tricyclic antidepressants, like, amitriptyline is likely to have a higher risk of increased side effects.

The usage of Jext in people with diabetes, Insulin levels have been found to decrease, resulting in increased sugar levels. Hence, diabetic patients need to be cautious.

Jext should be stored at room temperature, away from direct heat, humidity and light. Jext should not be used beyond its expiry date mentioned on the Jext pen. On expiry, replace the pen with a new one.

Jext is a prescription emergency device. You can buy Jext online. It is recommended that you always buy Jext online from a trusted online pharmacy like MedsNow. You can buy Jext from our online pharmacy, MedsNow, after getting proper medical online consultation with our experienced team of doctors and pharmacists. Alternatively, you can procure an independent prescription as well. The medication will be delivered conveniently to your doorstep. It is good to have online consultation because it will ensure that Jext is the correct medicine for your medical problem and you consume its appropriate dose as well.

What is the difference between JEXT and EpiPen?
Medicinally both Jext and EpiPen contain adrenaline. However, Jext is a new generation pen device. Jext has replaced EpiPen and is the most trusted device. Jext is a single-use auto-injector pen device.