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Evorel Patches (25, 50, 75 & 100 mcg)

Evorel patches are a type of Hormone Replacement Therapy. These patches contain a form of oestrogen called estradiol in various strengths that release gradually whilst you have them on ranging from 25 mcg per hour, 50mcg per hour, 75mcg per hour up to 100mcg per hour. The hormone passes through the skin into the body and spreads to give you relief from your symptoms.
Picture of Evorel Patches (25, 50, 75 & 100 mcg)
Picture of Evorel Patches (25, 50, 75 & 100 mcg)
Picture of Evorel Patches (25, 50, 75 & 100 mcg)
Picture of Evorel Patches (25, 50, 75 & 100 mcg)
Evorel 25
Evorel 100 for HRT Treatment
Evorel 75 for HRT Treatment
Evorel 50 for HRT Treatment
Picture of Evorel Patches (25, 50, 75 & 100 mcg)
Picture of Evorel Patches (25, 50, 75 & 100 mcg)
Picture of Evorel Patches (25, 50, 75 & 100 mcg)
Picture of Evorel Patches (25, 50, 75 & 100 mcg)
Evorel 25
Evorel 100 for HRT Treatment
Evorel 75 for HRT Treatment
Evorel 50 for HRT Treatment
Images for illustrative purposes only

Evorel Patches (25, 50, 75 & 100 mcg)

Evorel patches are a type of Hormone Replacement Therapy. These patches contain a form of oestrogen called estradiol in various strengths that release gradually whilst you have them on ranging from 25 mcg per hour, 50mcg per hour, 75mcg per hour up to 100mcg per hour. The hormone passes through the skin into the body and spreads to give you relief from your symptoms.


Evorel patches are an HRT treatment recommended to women experiencing the troublesome symptoms of menopause. Evorel is different from other HRT medications which are available in the form of tablets. It is a patch-based treatment which gradually releases hormones into the body. It is a suitable solution for women who are not comfortable with tablets or forget to take them regularly. All you have to do is replace the patch twice a week.

Menopause marks the stopping of oestrogen production in a woman's body. The deficiency of this crucial sex hormone in the body gives rise to a lot of symptoms, including hot flushes, sleep disturbances, vaginal dryness, depression, and osteoporosis. If these conditions get severe, you can use Evorel patches to supplement your body with the required amount of oestrogen. That will help relieve the symptoms that arrive with menopause, and you can go back to living a comfortable life.

Evorel patches contain the active ingredient estradiol hemihydrate, an oestrogen that your body is unable to produce naturally after the onset of menopause. Once you apply the patch on a clean and dry area of your skin, it gradually releases this hormone into your body, thereby overcoming symptoms like hot flushes, vaginal dryness, etc.

Women all over the world rely on HRT to offset the symptoms of menopause since for some of them these could last up to four years. Instead of suffering for such a long time, they prefer to use a patch-based treatment like Evorel. The primary advantage of using these patches is that it overcomes menopausal symptoms. It releases and restores the natural oestrogen level of your body since this hormone maintains optimum feminine health. In addition to this, Evorel patches also help women who can't use other medications for osteoporosis, a condition, which leads to the weakening of bones leading to frequent fractures.

Evorel patches are available in various strengths like 25, 50, 75 or 100. Despite this, your prescription will only recommend the lowest dose for you to start. The reason being, HRTs supplement hormones in the body, so you need to make sure that you are not overdoing it. Excessive oestrogen in the body could lead to complications and an increased risk of side effects.

Evorel is a prescription medication, and hence you must follow our advice carefully. Read the patient information leaflet thoroughly before using the patches.

Since this is a patch based Evorel supplement, you will apply it directly on the skin. The oestrogen passes from the skin slowly into the bloodstream. 

When to start using Evorelpatch? 

You begin using the patch when the menopausal symptoms become too distressing and start to affect your daily life. The patch will gradually increase the oestrogen level in the body to help relieve your symptoms.

Where to apply the Evorelpatch? 

Once you break open the protective pouch over the patch, apply it directly, without delay onto a clean, dry, cool patch of your skin. You can apply the Evorel patch onto a hairless area somewhere below your waist. It should remain covered under loose clothing and away from direct sunlight. 

Ensure that you: 

  • Do not apply the patch twice in the same spot 

  • Do not apply it anywhere near the breasts 

  • Do not apply it on cuts, spots, or inflamed skin 

  • Do not apply cream, moisturiser or talcum powder before using the patch 

  • Do not wear tight, elasticated waistband clothing when applying the patch 

How to put the patch on? 

  • Step 1 How to open and peel the Evorel patch?
    The notches work as a guide, and you have to tear along the two edges. Then, bend and peel half of the strip while the protective backing faces you.

  • Step 2 How to apply and press the Evorel patch?
    Apply the open half of the patch to your skin whilst slowly removing the remaining strip. Firmly press down the patch using your palm to ensure that it is secure. In case you cut the patch, you must use adhesive tape to secure the patch. 

Removing an Evorel patch 

  1. Start by peeling an edge of the patch away from the skin in a smooth motion.

  1. Slowly remove the entire patch and fold it in half with the sticky side facing inside.

  1. Dispose of it with the household rubbish. Make sure it remains out of the reach of children and pets.

  1. Do not flush used patches.

When you remove the Evorel patch, you might notice some adhesive remains on your skin. Use adhesive remover spray or wipes to remove the remaining adhesive without damaging your skin. It will go away with time.

Like every medication, Evorel patches also carry specific information, which you need to know and understand before beginning it. In addition to reading it here, you can also find these guidelines in the patient information leaflet, so make sure you read them thoroughly.? 

  • While you may experience spotting during the first few months of using Evorel patches, you will not necessarily face a monthly withdrawal bleed unless you are also taking progestogen tablets during the last few days of each month.? 

  • If you miss a dose, you might experience spotting, but it will subside soon. In case it continues after a few months of taking the medicine, or after stopping treatment, make sure to consult your doctor. 

  • You should undergo regular medical and gynaecological check-ups if you take any HRT to review its effects once a year with your doctor. 

  • You should be aware that women using HRT are ata very small increased risk of breast cancer, stroke and blood clots in the veins compared to those women not using HRT. You need to weigh this risk against the personal benefits of you taking HRT by thoroughly discussing it with our team. Consider investing in regular breast examinations and mammograms. You will also have to examine your breasts regularly and immediately report any changes in your breasts to a medical professional. 

  • If you have to undergo surgery, particularly abdominal surgery or orthopaedic surgery, your doctor may recommend you cease taking HRT usually four to six weeks prior.? 

  • Lastly, remember that HRT does not provide contraception for women who are considered fertile for two years after their last menstrual period if under 50, or for one year if over 50. If you are taking HRT and also require contraception, please discuss this directly with our team.

Not every woman undergoing the effects of menopause will experience the same type of relief upon using Evorel patches or any other HRT. Women with certain existing health conditions or medical histories will have to take extra precautions when starting with an HRT like this. These candidates include women who: 

  • Have a family history of breast cancer, fibrocystic breast disease, fibroids in the womb, endometriosis i.e. overgrowth of the lining of the womb, liver diseases, gallstones, or blood clots in the veins i.e. pulmonary embolism) 

  • Take medicines like warfarin for blood clot prevention 

  • Are suffering from systemic lupus erythematosus, a condition causing long-term inflammation of the skin and some internal organs 

  • Have suffered or are at risk of recurrent miscarriage 

  • Are suffering from obesity 

  • Smoke

  • Face severe varicose veins 

  • Have a history of high blood pressure (hypertension). 

  • Are risk heart failure 

  • Are having unhealthy amounts of triglycerides in the blood

  • Suffer from decreased kidney function, diabetes, migraines, epilepsy, or asthma 

  • Are at risk of developing an ear disorder that may cause hearing loss 

  • Have previously developed brown patches on their face due to pregnancy or negative interaction with contraceptive pills

Steer clear of this HRT if you are allergic to one or any of the ingredients in Evorel patches. Remember to inform your doctor or pharmacist if you have experienced an allergy to determine an alternative treatment for you. Listed below are groups of women who are unsuitable candidates of Evorel patches. These include women with: 

  • A recent encounter with or a family history of breast cancer, oestrogen stimulated cancer, endometrial hyperplasia 

  • Unexplained vaginal bleeding of unknown cause
  • Angina pectoris

  • Blood disorders leading to blood clots in the veins 

  • A blood clot in a vein of the leg or pulmonary embolism in the lungs 

  • Inflammation in a vein that has been caused by a blood clot

  • A recent stroke or heart attack 

  • Active liver diseases such as hepatitis, liver cancer 

  • Pregnancy or breastfeeding 

  • Rare hereditary problems of galactose intolerance, fructose intolerance, etc

Like every other medication, Evorel patches do have their own set of side effects. While most of the reactions listed below are commonly occurring, not every woman taking this HRT needs to experience a side effect. Some of the side effects include: 

  • Headaches 

  • Breast tenderness 

  • Painful periods 

  • Irritation on the area of the skin where the patch is applied 

  • Problems with your menstrual cycle 

  • Difficulty sleeping or feeling dizzy

The ingredients in Evorel patches tend to react with the contents of some medications giving rise to complications. Hence, it becomes crucial that we know if you are currently taking, or plan to take, medicines like: 

  • aprepitant 

  • rifampicin 

  • ritonavir 

  • bosentan 

  • eslicarbazepine 

  • phenytoin 

  • fosaprepitant 

  • fosphenytoin 

  • carbamazepine 

  • efavirenz 

  • oxcarbazepine 

  • rifabutin 

  • rufinamide 

  • the herbal remedy St John's wort (Hypericum perforatum) 

  • topiramate 

  • modafinil 

  • nevirapine 

  • phenobarbital 

  • primidone 

You can order Evorel patches online from a trusted clinic like MedsNow to ensure that you receive only the best and safest products. You will have to undertake an online consultation to ensure that Evorel patches are the ideal remedy for your medical needs. The consultation works as a prescription for your order, and you won't have to visit a doctor for one. Upon confirmation, your order will be dispatched and delivered discreetly to your doorstep.

Store this medication away from the sight and reach of children. Keep it in a place that is cool and dry while being away from direct heat and light.


Evorel Sequi 

Evorel Conti 

Contains only estradiol (oestrogen)  

Contains estradiol (oestrogen) and norethisterone (progestogen) 

Contains estradiol (oestrogen) and norethisterone (progestogen) 

Prescribed for women who have had a hysterectomy? 

Prescribed for women without hysterectomy 

Prescribed for women without hysterectomy 

Bioidentical form of HRT 

Non-bioidentical HRT 

Non-bioidentical HRT 

Each pack contains 8 patches containing only estradiol  

Each pack contains four patches containing only estradiol and four containing estradiol and norethisterone 

Each pack contains 8 patches containing both estradiol and norethisterone 


Combined form of HRT 

Continuous form of HRT 

Is it safe to use Evorel patches if pregnant or breastfeeding?
No, pregnant and breastfeeding mothers should not use these patches.

Are Evorel patches safe?
Clinical research indicates that as a short-term treatment, the benefits outweigh the risks even though, there are few risks associated with HRT-based treatment of menopausal symptoms, including a higher risk of certain cancers.

Will I need to take Evorel for the rest of my life?
You won't have to continue with the treatment for long because all the HRT medications are only recommended as a short-term solution to relieve menopausal symptoms.?

What if the patch falls off?
You can either try to reattach it or use a new one till your next patch is due.

What if I forget to change the patch?
Don't worry, you can apply a patch as soon as you remember and then keep following your regular patch change schedule.

What do you do in the case of an overdosage?
Since it is a patch, overdosing with a single one is highly unlikely. If you use two by mistake, you might experience symptoms of breast tenderness, nausea and irregular bleeding. Reverse the overdose by removing the extra patch and getting it checked by a medical professional.

Can I go swimming with the patch on?
Yes, you can carry on with your activities with the patch. In case it falls off, you can either stick it back to a different area or use a new patch.

Do Evorel patches cause weight gain?
Yes, weight change is a common side effect of Evorel patches since it supplies oestrogen to the body. A slight fluctuation in this hormone can cause weight gain.

How long do Evorel patches take to work?
It takes about 4 hours for the oestrogen to reach your bloodstream and begin its work. The effects of the patch can last up to 3 to 4 days.

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