Every woman around the age of 45-55 experiences menopause, a condition in which their ovaries start to produce lesser oestrogen. That hormonal imbalance leads to several bodily changes and reactions like hot flashes on the face, neck and chest, irregular menstrual cycle, night sweats, weight gain, thinning of hair and mood changes. Premique, also known as Premique Low Dose, is a combined HRT since it contains both the primary female sex hormones, oestrogen and progesterone. The medication helps restore the lack of oestrogen in the body, thereby relieving all the symptoms of menopause.
Each tablet of Premique contains both the female sex hormones, i.e. a natural form of oestrogen (conjugated oestrogen) and progesterone (medroxyprogesterone acetate). Since the composition of conjugated oestrogens is the same as the natural oestrogens produced by your body, it causes the body to respond in a similar way. During menopause, when your body is facing a shortage of these essential hormones, the tablets work to replenish the hormonal balance.
Women, who are, suffering from severe menopausal symptoms that are disrupting their daily lives are recommended to begin an HRT like Premique to alleviate their miseries. With Premique, you will be able to pass through severely discomforting signs of menopause and the suspension of the menstrual cycle in a more comfortable way. The primary role of this medication or any other HRT is to ease the symptoms of menopause and help you lead a normal life. The medicine will not produce a monthly bleed because the doses are constant. However, the medroxyprogesterone, present in Premique, balances the effect of extra oestrogen on the endometrium.
Menopause is a time in a woman's life that brings a lot of changes within and outside the body. In addition to dealing with symptoms like hot flushes, vaginal dryness, weight changes, etc., they also face an increased risk of developing conditions like osteoporosis which cause thinning or weakening of bones, resulting in frequent fractures. That is where HRTs like Premique enter the picture to save the day. It restores female sex hormones like oestrogen in the body and helps avoid osteoporosis.
Your doctor will prescribe the lowest possible dose as a beginner course of this treatment. Each tablet of the lowest dose contains 0.3mg of conjugated oestrogens and 1.5mg of medroxyprogesterone acetate. Always stick to your doctor's instructions when taking the medication and do not alter the dosage on your won.
Premique is available as a calendar pill, i.e. you will take one pill each day for 28 days continuously without a break. In case you find no change in your symptoms because the dosage is too low, you can talk to your doctor for a higher dose. Although you will begin with the lowest dose for as short a time as possible, you can try a higher dosage if your body can tolerate the higher amount of hormone addition.
For consumption, you need to swallow your tablet whole, with plenty of water. You can take it with or without food but do not suck, crush or chew the tablet. Make sure you read the patient information leaflet thoroughly before starting with the medication.
Similar to all other medications, Premique comes with its own set of messages and guidelines for safer use. Carefully go through the listicle below.
While you may experience spotting during the first few months of taking Premique, you will not necessarily face a monthly withdrawal bleed unless you are also taking progestogen tablets during the last few days of each month.
If you miss a dose, you might experience spotting, but it will subside soon. In case it continues after a few months of taking the medicine, or after stopping treatment, make sure to consult your doctor.
You should undergo regular medical and gynaecological check-ups if you take any HRT to review its effects once a year with your doctor.
You should be aware that women using HRT suffer an increased risk of breast cancer, stroke and blood clots in the veins. You need to weigh this risk against the personal benefits of you taking HRT by thoroughly discussing it with your doctor. Consider investing in regular breast examinations and mammograms. You will also have to examine your breasts regularly and immediately report any changes in your breasts to a medical professional.
If you have to undergo a surgery, particularly abdominal surgery or orthopaedic surgery, your doctor may recommend you cease taking HRT usually four to six weeks prior.
Lastly, remember that HRT does not provide contraception for women who are considered fertile for two years after their last menstrual period if under 50, or for one year if over 50. If you are taking HRT and also require contraception, you will have to opt for a non-hormonal method such as a condom or contraceptive foam.
This section will highlight specific groups of women who should take extra precautions with HRT medications like Premique. The reason being, it could affect or trigger some of the existing health conditions in the body. These include women with:
Risk or history of developing oestrogen stimulated cancers like breast cancer, or benign breast lumps, fibroids in the womb, endometriosis, endometrial hyperplasia, blood clots in the veins, gallbladder disease, or blood disorders called porphyrias
a medicated dose of anticoagulants like warfarin to prevent blood clots
Severe varicose veins
High blood pressure
High cholesterol or triglycerides levels in their blood
a long-term condition called systemic lupus erythematosus (SLE)
Migraines or severe headaches
a tendency to develop irregular brown patches on the skin should minimize their exposure to the sun or UV light while taking HRT
Yes, there are certain risks you already face that could get triggered with an HRT. So Premique becomes an unsuitable treatment option for you in that case. Women who should steer clear of this medication include the ones with:
A recent encounter with or a family history of breast cancer, oestrogen stimulated cancer, endometrial hyperplasia
Vaginal bleeding where the cause remains unknown
Blood disorders leading to blood clots in the veins
A blood clot in a vein of the leg or pulmonary embolism in the lungs
Inflammation in a vein that has been caused by a blood clot?
A recent encounter with a stroke or heart attack
Active liver diseases such as hepatitis, liver cancer
Pregnancy or the ones who are breastfeeding
Rare hereditary problems of galactose intolerance, fructose intolerance, etc
This section will list down all possible side effects of the medication you should look out for to avoid any complications. The most commonly occurring side effects of Premique are:
breakthrough bleeding or spotting
breast tenderness, swollen breasts
muscle and joint aches, leg cramps
There are various medicines whose ingredients interact negatively with each other leading to complications. That is why it would be wise to inform your healthcare provider about all the other medications you are taking currently before beginning with Premique. It affects medicines for:
Cushing’s syndrome, i.e. Metyrapone
Breast cancer, i.e. Aminoglutethimide
Herbal remedies containing St John’s Wort
The ideal way to order your medication from the comfort of your home is to place an order with trusted online pharmacies such as MedsNow. It is crucial to choose a suitable supplier to ensure that you receive a reliable product. Since Premique is a prescription-only HRT, you will need to undertake a quick, free, and simple online consultation, which will help determine that Premique is an ideal treatment option and will work as a prescription defining your eligibility for the medication. Post that, your order will be delivered to you discreetly.
You should store Premique in a cool, dry place away from direct heat and light. Make sure it remains hidden from the sight and reach of children.
What if I take too much Premique?
Like every other medication, overdosing on Premique can lead to several side effects. Too much Premique could cause nausea, vomiting, breast tenderness, dizziness, abdominal pain, etc.
What if I forget to take Premique?
Take the missed dosage as soon as you remember and then continue with your dosage schedule as usual. If you miss more than one tablet, do not take double the usual dose. Only consume the most recent one.
Is Premique HRT still available?
Yes, Premique HRT is available, and you can place your order for them online via trusted sellers like MedsNow.
Can I take Premique Low Dose if I am pregnant?
No, please do not consume the medication when pregnant. Pregnant and breastfeeding moms are unsuitable candidates for Preminique Low Dose.
(GPhC Reg: 2061101)
(GPhC Reg: 2086766)